The short answer is YES.  ...

The short answer is YES.  The long answer is yes BUT only a well designed floating bed systems.

For example, some contaminants eg mercury or some of the gross radioactive chemicals are not conducive to the biological treatment and need a supplementary chemical process.

With regard mine site spillage and clean up, any and every chemical can be removed, it takes money and determination, the answer can only be yes when their is a genuine commitment by the community and the mining company if they share a responsibility to rectify the situation.

Each project will be different.  My recommendation is to obtain competent consulting advice from a water treatment engineer with such experience in this field.  I happen to know such a person!