I could be wrong but this ...

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I could be wrong but this honestly sounds very much like a broken seal between your membranes or a membrane failure. A couple questions:  1. How often do you probe your RO membranes for conductivity in the permeate stream...I make sure that this is done monthly on all our plants and is the absolute fastest way to determine which membrane unit is causing your failure 2. Do you have an ORP (oxidation reduction potential) sensor in front of your high pressure pumps because this type of sudden failure sounds like a non-dissolved particle or oxidant was allowed into your RO units and repuptured one of them.    If you've done these 2 already I can ask more specific questions but in would start with probing and find the culprit membrane and remove and replace it immediately.    Kurt